PKIN Reference > Reference Tissue Models

PKIN features the following list of reference models which are mostly used for the analysis of receptor ligand studies:

Model Name	Description
4 Parameter Reference Tissue Model	4 Parameter Reference Tissue Model by Lammertsma et al.
SRTM	Simplified Reference Tissue Model by Lammertsma and Hume
SRTM2	Modification of Simplified Reference Tissue Model by Wu and Carson to reduce BP bias induced by noise
MRTM0	Original Multilinear Reference Tissue Model by Ichise et al.
MRTM	Multilinear Reference Tissue Model by Ichise et al modified to reduce bias induced by noise
MRTM2	Multilinear Reference Tissue Model by Ichise et al modified to reduce bias and variability induced by noise
Logan Non-Invasive	Reference tissue method which is based on an average k2
2 Tissue Reference Model	Watabe's reference tissue model with a 2-tissue compartment model in the reference region
MP4A RLS (Nagatsuka)	Multi-linear Reference Tissue Model for [11C]-MP4A (RLS)