Voxel-wise TAC modeling in PKIN

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Voxel-wise TAC modeling in PKIN

After transfer from the PVIEW tool the voxel-wise TACs are arranged in the Region list labeled with the VOI name followed by the voxel coordinate in the image.

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In the same way as for modeling with average TACs the blood and plasma data have to be loaded, or a reference approach has to be used. The whole PKIN functionality is then available for modeling. For instance, a few TACs can be averaged, a 1-tissue compartment model fitted as illustrated (after loading the blood data), propagated to all TACs using the Copy to All Regions entry Model & Par, and fitted with Fit model, all regions. Another possibility is to transfer the averaged TACs also from PVIEW, use them for setting up the proper model, propagate and fit.